Use of the Olfactory System to Understand Neurological Disease

The Wet Lab is hosting a neuroscience lecture at the La Jolla Riford Library on Tuesday, April 4th from 630pm – 730pm.  Samantha Jones, a graduate student in UCSD’s biomedical sciences program will discuss how mutations in genes associated with RNA degradation pathways can cause neurological disease.


Intellectual disability (ID), formerly called “mental retardation,” is estimated to affect ~2% of the world’s population and have a considerable socio-economic impact, yet its underlying cause is often unknown. My work focuses on one form of intellectual disability and how it is caused by mutations in a gene (UPF3B) important for proper RNA decay. I hope to understand the effect of UPF3B depletion on the nervous system by using the olfactory system (our smell center) as a model of neurogenesis.

This event is part of the San Diego Wetlab’s citizen science lecture series held every first Tuesday at 6:30pm at the La Jolla Library and every third Thursday at 6:30pm at the Downtown Library.   Please check the San Diego library system events page for location details and changes in the upcoming schedule.


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